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The decreased NADPH production results in insufficient reduction of oxidized glutathione disulfide (GSSG) and Prdx2, thus rendering the antioxidant system less effective ( Classes of Mutation and Spectrum of Deficiency G6PD deficiency is a heterogeneous condition with 217 mutations reported as of 2016

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H., Chang, B., Choi, E

doi: 10.1186/1476-5918-7-6 19 The Optimum Health Clinic (OHC)